HELLO everyone. now i would like to share about the most well known disease. This disease is very familiar in our country
and it is recognize as a rich-disease. It is because most of the rich family
has been attack by this disease in a mean time.(perhaps not)
Now I would like to share with all of you regarding the
statistic of gout disease around the world. During 2004,
about 30 % of gout patient die in
Thailand, 24 % in US, 17% in Mexico, 13% in Japan, 8% in Brazil and Korea.
Before I explain further, let me explain what is uric acid.
Uric acid basically the end product of purine metabolism in the cell and
tissue. Purine can be found in all type
of foods that we eat every day. Then, the consumption of purine will undergo
metabolism that will produce uric acid.
What is gout disease actually. It is a state where
recurrent inflammation happened due to deposition of urate crystal at any
joint. Then it will cause painful attacks in the joints such as knee, ankle,
foot and arm. If left untreated, the
attack will become more frequent, more prolonged and more generalized.
For over 2000 years ago, gout disease is a very well know
disease and it is famous with name of king of the disease. It is because of the
overindulgence of fatty food and alcohol. . That’s why I said early that this disease commonly happen in rich family because they eat plenty of
foods. Besides, animal also has tendency
to get a gout disease which is a very well known not only by human but also
animals can suffer from this disease.
One researcher has found that about 80 % of patients will got an
attack of gout at the big toe and 20% get an attack of gout disease at more
than one joint, maybe at knee of arms.
Do you have any idea why I explain about uric acid just
know? It is because due to increase in the level of uric acid in the body will
lead the formation of gout disease. . that’s the main reason why the gout disease
occurs. Besides, consume food that contain high content of uric acid also will
lead to this problems. Besides, if the
patient has a kidney problem, also lead to gout disease because the kidney
unable to excrete out excess uric acid in body, thus cause accumulation of uric
acid in the body.
Liver problem also can lead to this problem because when
liver is damage, it cant metabolize uric acid in the body, thus also cause
accumulation of uric acid, then lead to formation of monosodium urate crystal
in the joints. Then, a researcher have
found that 1 out of 4 gout patients have a family history of gout disease, this
means that the disease can be inherited by one generation to other generation.
Other drugs such as diuretics drugs also can cause accumulation of uric acid in
the body because this drugs can interfere with the normal excretion of uric
acid.
The last factor that can cause gout disease is environmental
factors such as stress, physical injury, unusual physical exercise, severe
illness, surgery.
Example of food that contain high content of
uric acid include sea foods, mushrooms, lentils, organ meats, spinach, oat, yeast product and many more.
Who is at risk of gout disease? It is you, me , teacher or
who? It is men, women or child. Research have found that men has high content
of uric acid compares to women. So men has high tendency to expose to this
disease. Men typically will be attack by
gout disease at the age of 30-50 years old. Whereas women is after
menopause. It is because after
menopause, level of uric acids in women tends to increase higher than men. Then , a very few cases is reported about the
gout attack among teenagers and children.
Besides, obese people also has high tendency to suffer from this
disease. Then also alcoholic people.
Now, how do we know that we got an attack of gout disease.
The sign and symptoms of this disease is easily recognize because we can see
and feel it clearly. An acute attack of gout disease often occurs night or
early in the morning that will reach peak within a few hours. For example
swelling at the affected area. This is the first symptom that present itself.
You will feel like you feet would explode anytime. This swelling may affect more than one joint.
Then, the affected area will become redness, tenderness and warmth due to
build-up of uric acid crystals in the joints.
Then of course you will feel intensely pain at the affected
area. Even touched by a blanket or clothers, you can’t tolerate feel of
pain. Then you skin may become peel and
itch because the swelling that occurs earlier. Once the swelling subsides, the
skin will become dry. The last one is
the presence of nodules due to accumulation of monosodium urate (MSU) crystals. It is
a white compound that forms after uric acid composite in the joints.
In the treatment of gout disease, there are three important
steps. We have to follow this steps in order to reduce the attack of gout
disease.
THE FIRST steps we have to reduce the pain and inflammation.
To treat this we can useda NSAIDs drugs. For example ibuprofen, indomethacin
and diclofenac. The short half life
drugs such as ibuprofen and indomethacin is commonly used because of its rapid
action, but it must be used coutiosly in
patients with peptic ulcer gastric heamorrhage and renal insufficiency.
Besides we also can used colchine when NSAIDs drugs is not
effective even though it can cause diarrhea.
The if the pain does not reduce, we can used corticosteroid drugs by
injected the drugs to the affected area to reduce the inflammation.
THE SECOND STEPS is by life style modification to reduce
another attack of gout disease. Patients
can alter diet, reduce weight, and
reduce alcohol consumption
THIRD STEPS is by lowering the uric acid level in the
body. This steps used for a long term
treatment. It can be used when no acute attack is occurs. Example of drugs is
allopurinol and probenecid. Allopurinol can reduce the uric acid production in
our body. It is most helpful in patients with a very high level of uric acid in
the body or they have kidney failure. Probenecid is a uricosuric acid, it will
increase the excretion of uric acid in the body. This drugs may not affective
in kidney failure patients.
As a conclusion, we can avoid this disease from attacking
us. Once the symptoms is arises, we have to go straight away to the doctor. So
that proper management could be assign.
No boby want to live in pain including me, because it can effect all
things in our life right. So we have to take a proper action to reduce the pain
such as apply an ice at the swelling joint.
A good gout treatment plan is needed to manage this disease properly.
